The AIRC 2021 calendar is a tribute to the discoveries made in the field of cancer research. Creating the various illustrations, the oncological discovery is connected with the desire and curiosity that drives man to seek and discover new scenarios. From the abyss to the peaks, from the desert to the glaciers, the elements discovered in cancer research will be catapulted into surprising environments to celebrate research in general and highlight how discoveries made in one area can serve in other sectors and, therefore, how research can be a universal glue.